Podbit · Bloomberg Intelligence
When Dave Ricks took over as CEO, Eli Lilly was one of the slowest drug developers in the industry. He mandated speed above all else. The result: tirzepatide went from lab to approval in about 5 years — less than half the old timeline.
Where this was said
At 28:38 · chapter starts 26:20
Madison Muller recounts Eli Lilly's history, its dry spell, and how GLP-1 weight loss drugs transformed it into the world's most valuable healthcare company under CEO Dave Ricks. [1] — Madison Muller "Eli Lilly had a dry spell bad enough to tank its stock and trigger CEO turnover. Then weight loss drugs arrived and transformed it into the…" 27:05
Eli Lilly, founded 150 years ago, is now the most valuable healthcare company in the world, transformed by the success of its GLP-1 weight loss drugs.
Eli Lilly had a dry spell bad enough to tank its stock and trigger CEO turnover. Then weight loss drugs arrived and transformed it into the world's most valuable healthcare company. The comeback story of the decade in pharma.
Anxiety is not fear. Fear has an object — a wolf, a threat. Anxiety is the vertigo of standing at the edge of infinite possibility and knowing that choosing any one thing closes off all the others. Kierkegaard argued that the depth of your anxiety is proportional to the depth of your potential.
AI nailed Andrew Huberman's vertigo-vs-low-blood-pressure diagnosis because that pattern has been reported millions of times. But every patient's liver is different and data on liver surgeries is scarce worldwide — making solo robot surgery dangerous. The rule is simple: data abundance means AI can help; data scarcity means keep the human in the loop.
Fei-Fei Li's father had liver surgery performed by a da Vinci robot guided by a surgeon. The result: 10 times less blood loss than a typical procedure. This isn't replacement — it's the gold standard of human-machine collaboration, where the human's judgment and the robot's precision combine.
US drug overdose deaths fell from 110,000 to roughly 70,000 — the biggest CDC-recorded single-year drop ever. Men's rates fell 27% in one year, and the steepest decline of all was among 15–24-year-olds, down 37%. The crisis narrative around young men needs to make room for signs of genuine progress.
Kessler thought his grief expertise would protect him. It didn't. When his son David died unexpectedly, he found himself on the floor — and eventually realized that acceptance alone wasn't enough. That unmet need became the sixth stage: finding meaning.
Grief isn't just death — it's any unwanted change. Kessler lectured at Coca-Cola and General Mills not because they had lots of funerals, but because change management is grief management. People who grieve well live well.
Witnessing someone's grief isn't just emotional support — it's an essential act of healing. Kessler argues grief is a severance and connection heals it. But real witnessing has two steps: seeing the pain AND affirming the person's capacity to recover.
Avoiding grief isn't free — it's exhausting. Kessler's beach ball metaphor nails it: pushing a small balloon down is easy, but holding a massive beach ball underwater takes constant, draining energy. Unattended feelings don't disappear; they just consume you.
Most people try to control their environment to avoid triggers. Kessler flips this entirely: triggers aren't problems to manage around — they're a detailed map to your pain and your healing. Every trigger points directly to what needs attention.
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