Modern Wisdom

Podbit · Modern Wisdom

Who You Meet Down America’s Forgotten Backroads - Peter Santenello - #1132

Explore episode Aug 3, 2026

Where this was said

Appalachia, OxyContin & The Fentanyl Pipeline

At 42:35 · chapter starts 36:55

Appalachia's drug crisis didn't come from nowhere. Peter met a fourth-generation coal miner who described being among the first people prescribed OxyContin — a drug developed by the Sackler family that was, in effect, road-tested on a population accustomed to extreme physical pain. When the coal jobs began to leave, the physical pain became psychic pain, and the addiction intensified. Peter describes the stark binary he sees in the region: people are either working incredibly hard and getting by, or deep in poverty and drugs — there is almost no middle. Fentanyl arrived roughly five or six years ago and hit hard, and the region's remoteness means there are no easy economic escape routes. The inner-city kid, Peter notes, has subway access to an entire economy. The Appalachian kid has nothing nearby to tap into.

Health & Fitness
OxyContin to Fentanyl: The Drug Pipeline That Destroyed Appalachia

Who You Meet Down America’s Forgotten Backroads - Peter San… · Aug 3, 2026 Health & Fitness

Appalachian coal miners were among the first prescribed OxyContin. The physical pain was real, but when the jobs left, the psychic pain amplified the addiction. Fentanyl followed five or six years ago. The fallout — poverty, crime, broken families — still hasn't cleared, and Peter sees it as a deliberate corporate exploitation of a desperate population.

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