On Purpose with Jay Shetty

Podbit · On Purpose with Jay Shetty

Dr. Chris Palmer: Your Diet Could Be Causing Anxiety, Depression & Brain Fog (6 Simple Changes to Make Today)

Explore episode Jul 3, 2026
Health & Fitness
What THC Is Actually Doing to Your Brain

Dr. Chris Palmer: Your Diet Could Be Causing Anxiety, Depre… · Jul 3, 2026 Health & Fitness

THC impairs mitochondrial function, causes measurable cognitive and motivational decline, and raises the risk of developing schizophrenia or bipolar disorder by approximately four times. The vaping transition from cigarettes often makes nicotine addiction worse, not better, because nicotine concentrations are dramatically higher.

Where this was said

Exercise Doesn't Have to Be Extreme to be Effective

At 36:00 · chapter starts 35:46

The conversation moves into specific harmful substances, and Palmer is emphatic and specific. THC, the active compound in marijuana, interacts with brain receptors throughout the body, impairs mitochondrial function, causes measurable cognitive and motivational decline, and epidemiological data suggests it increases the risk of developing schizophrenia or bipolar disorder by approximately four times. He uses the image of the unmotivated, unbothered teenage boy in his parents' basement as a clinical illustration, not a moral judgment. On vaping, he makes a nuanced harm-reduction concession — if you are smoking cigarettes and can't stop, switching to vaping is marginally better — but warns that nicotine concentrations in vapes are often stratospherically higher than in cigarettes, deepening addiction. Alcohol, he adds, tells a similar story to THC: not good for brain, not good for metabolic health.

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