Podbit · Modern Wisdom
Tim Ferriss has taken Avmacol — a sulforaphane precursor that activates your body's own detoxification pathways rather than supplying an external antioxidant — for nine months, primarily for neuroprotection given his family's Alzheimer's history. An unexpected side effect: more skin compliments than he's ever received.
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At 2:12:00 · chapter starts 2:11:35
Tim Ferriss produces Avmacol, a tablet containing a glucoraphanin precursor and myrosinase enzyme that the body converts into sulforaphane. He has been taking it for nine months, motivated primarily by multiple family members with Alzheimer's and his desire for neuroprotection — alongside xylitol mouthwash for the same reason. He notes that sulforaphane activates NRF2 pathways — biologically plausible, reasonably safe, interesting human data, but not a slam-dunk clinical intervention. An unexpected bonus: Ferriss has received more compliments about his skin in the past six months than ever before, and attributes it tentatively to Avmacol and Timeline's Urolithin A. Chris Williamson then drops a bombshell: University of Michigan researchers have amended the foundational microplastics study, finding that latex and nitrile gloves worn during sample collection shed stearate particles chemically identical to polyethylene that the instruments couldn't distinguish from plastic. The credit-card-per-year consumption figure may be off by a factor of 100.
Tim Ferriss has taken the sulforaphane-precursor supplement Avmacol for nine months primarily for neuroprotection, given multiple family members with Alzheimer's, and has noticed unexpected improvements in skin tone.
University of Michigan researchers found that latex and nitrile gloves worn during microplastics sample collection shed particles chemically identical to polyethylene, suggesting the widely cited credit-card-per-year consumption figure may be inflated by up to 100 times.
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