Podbit · Modern Wisdom
Post-SSRI Sexual Dysfunction causes permanent nervous system injury: genital numbness, loss of orgasm, and sudden-onset chemical asexuality in women who stop taking antidepressants. 50–70% of patients on SSRIs experience sexual side effects, and for some it never reverses.
Where this was said
At 12:36 · chapter starts 10:42
17% of 18–24-year-olds are on antidepressants. Isabel shares a story of a woman prescribed SSRIs at age 7. A PSSD testimony reveals permanent genital numbness affects 50–70% of SSRI patients. [1] — Isabel Brown "Post-SSRI Sexual Dysfunction causes permanent nervous system injury: genital numbness, loss of orgasm, and sudden-onset chemical asexuality…" 12:36
Nearly 17% of Americans aged 18–24 are currently prescribed antidepressants, significantly above the 12% rate for all adults.
50 to 70% of all patients taking SSRIs will experience sexual side effects, and for some these effects become permanent after stopping the drug.
Unlike the military where generals can't immediately join defense contractors, there are no equivalent protections preventing executives from cycling between Pfizer and the FDA. This revolving door shapes which drugs get approved and which side effects get buried.
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US drug overdose deaths fell from 110,000 to roughly 70,000 — the biggest CDC-recorded single-year drop ever. Men's rates fell 27% in one year, and the steepest decline of all was among 15–24-year-olds, down 37%. The crisis narrative around young men needs to make room for signs of genuine progress.
Kessler thought his grief expertise would protect him. It didn't. When his son David died unexpectedly, he found himself on the floor — and eventually realized that acceptance alone wasn't enough. That unmet need became the sixth stage: finding meaning.
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Running from pain doesn't leave it behind — it accelerates the chase. Whatever we run from pursues us, and whatever we face transforms us. Both Kessler and Lewis Howes testify to knowing both roads firsthand.
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