Podbit · The Diary Of A CEO with Steven Bartlett
Transplant a tumour cell nucleus into a healthy enucleated cell: no cancer. Transplant a healthy nucleus into a tumour cell's cytoplasm: cancer. The cancer lives in the cytoplasm — in the mitochondria — not the DNA. This experiment should have rewritten oncology. It hasn't.
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At 1:07:37 · chapter starts 1:07:12
This is the chapter where Seyfried delivers the kill shot to the somatic mutation theory. The experiment is elegant and unambiguous: remove the nucleus from a cancer cell and place it into an enucleated healthy cell — no cancer develops. The cell functions normally. Then take a healthy nucleus and place it into the enucleated cytoplasm of a cancer cell — dysregulated cell growth follows. [1] — Thomas Seyfried "Transplant a tumour cell nucleus into a healthy enucleated cell: no cancer. Transplant a healthy nucleus into a tumour cell's cytoplasm: ca…" 1:07:37 The cancer is in the cytoplasm, where the mitochondria live, not in the DNA. This experiment has been replicated, it has been published, and the National Cancer Institute's website still describes cancer as 'a genetic disease.' Seyfried's frustration with this cognitive dissonance is palpable: the science exists, the proof is there, and the field is protecting a broken system. His analogy to the geocentric theory of the solar system — held for 1,800 years by the power of the Catholic Church despite accumulating contradictory evidence, until Copernicus, Kepler, and Galileo forced a paradigm shift — is pointed and apt.
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