Quote · TED Talks Daily
The deadly threat affecting millions — and how to prevent it | Drew McCartor
Where this was said
The Neuroscience: How Lead Builds Dead Ends in the Developing Brain
At 13:10 · chapter starts 12:20
To explain why Saim's memory cannot be restored, McCartor walks the audience through what lead actually does inside a child's brain [1] — Drew McCartor "Lead mimics calcium in the developing brain, tricking it into using lead instead of calcium to build neural connections. The result is a ch…" 12:40 . He asks us to picture the developing brain as a new city under construction — and calcium as the expert city planner, directing neural crews to build synaptic roads and bridges that enable learning, memory, and impulse control. Lead, he explains, is a chemical impostor: it mimics calcium so convincingly that the brain uses it in place of the real thing. But lead is a terrible planner. It directs those same neural crews to build dead-end streets and bridges to nowhere — a chaotic, non-functional network that, once formed, cannot be torn down and rebuilt. The damage is permanent by design, because the brain does not re-lay its foundations. This mechanism, McCartor reveals, is not a rare misfortune: more than 1 billion children and teenagers worldwide currently have blood-lead levels above the WHO intervention threshold [2] — Drew McCartor "More than 1 billion children and teenagers worldwide have blood-lead concentrations above the WHO intervention threshold. That's 1 in every…" 13:40 . That is 1 in 3 children on Earth. He pauses and lets the number sit: 'A billion. That's one in three. Now imagine you're looking at your kids, and you have to choose. Which one?'
Lead mimics calcium in the body, causing the brain to use it in place of calcium for building neural connections, resulting in permanent brain damage.
Lead mimics calcium in the developing brain, tricking it into using lead instead of calcium to build neural connections. The result is a chaotic network of dead-end streets and bridges to nowhere — and once built, the damage never reverses.
More than 1 billion children and teenagers worldwide have blood-lead concentrations exceeding the WHO threshold for intervention — that's 1 in 3 kids.
More than 1 billion children and teenagers worldwide have blood-lead concentrations above the WHO intervention threshold. That's 1 in every 3 kids on Earth — and almost all of them live in low- and middle-income countries.
The average child in low- and middle-income countries has lead exposure high enough to lose an estimated 4 to 5 IQ points.
At current average exposure levels, lead is sufficient to shift the global intelligence curve downward — cutting in half the number of children with IQs above 130, and increasing by 50% those with IQs below 70. We are engineering a less capable humanity by inaction.
