Snapshot · Modern Wisdom
When estrogen drops, dopamine drops with it, making emotional regulation harder — meaning women are biologically more rejection-sensitive for roughly two weeks of every month.
Where this was said
At 17:39 · chapter starts 16:54
Returning to a point she flagged earlier, Dr. Hamdani makes the case that hormones may be the most overlooked variable in emotional sensitivity. Estrogen and dopamine are directly coupled: when one drops, so does the other. For women, this means the hormonal cycle — monthly fluctuations, pregnancy, postpartum, perimenopause — produces multiple biologically distinct versions of emotional experience within a single lifetime, and within a single month. Testosterone, meanwhile, acts as a protective buffer against emotional sensitivity in men. As it naturally declines in their 50s and 60s, many men are hit by an unfamiliar surge of emotional feeling they have spent their entire lives being trained not to acknowledge or process. [1] — Dr. Sasha Hamdani "As estrogen drops, dopamine drops with it — and dopamine is what lets you regulate your emotions. For women, this happens on a monthly cycl…" 17:15
As estrogen drops, dopamine drops with it — and dopamine is what lets you regulate your emotions. For women, this happens on a monthly cycle, during pregnancy, and through perimenopause. For men, falling testosterone in their 50s and 60s creates an unexpected surge in emotional sensitivity they have no framework to handle.
Testosterone acts as a buffer against emotional sensitivity, but as it drops in men in their 50s and 60s, many experience a surge of emotional sensitivity they have no tools to handle.
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