Snapshot · The Diary Of A CEO with Steven Bartlett
61% of UFC fighters have stated they worry about potential long-term brain damage from the sport, with about 21% noticing differences in their brain function after their fighting career.
Where this was said
At 1:16:30 · chapter starts 1:11:20
Bartlett pivots to the physical cost of fighting, sharing data he gathered from interviewing what he describes as a leading CTE researcher. The numbers are stark: older adults with head trauma history face a 230% greater Alzheimer's risk; 61% of UFC fighters worry about long-term brain damage; and a 2023 study found over 40% of contact sport athletes who died before 30 had CTE. [1] — Dustin Poirier "A neurological scan of Poirier's brain revealed thinning and a separated brain septum, with his neurologist concerned that the left and rig…" 1:15:50 Poirier then reveals that his wife's concern about behavioural changes prompted a neurological scan with contrast dye, which showed thinning in the back of his brain and a separated septum pellucidum — a structure whose splitting the neurologist believes is reducing communication between brain hemispheres. He can't be diagnosed with CTE while alive, but the physical evidence is there. He notes that spontaneous decision-making — betting $5,000 impulsively, getting drunk in the airport — might link to brain changes, though he's careful not to use it as an excuse.
A neurological scan of Poirier's brain revealed thinning and a separated brain septum, with his neurologist concerned that the left and right hemispheres may not be communicating normally. CTE can only be definitively diagnosed posthumously, but the physical changes and his wife's reports of behavioral shifts are concerning. A 2023 study found over 40% of contact sport athletes who died before 30 already had CTE.
Older adults with a history of traumatic brain injuries have a 230% greater risk of developing Alzheimer's disease than those without such a history.
A 2023 study found that more than 40% of brains from contact sport players who died before age 30 showed signs of CTE.
A neurological scan revealed brain thinning and a separated brain septum in Poirier, with the neurologist suggesting the left and right sides of his brain may not be communicating smoothly.
Poirier and Jolie were packing up their South Florida home when they saw a news story about a police officer killed near where they went to school, leaving behind a family. They auctioned his fight gear to help the family, then kept going. What started as eBay listings became a formal nonprofit with an annual back-to-school drive, international water well projects in Uganda, and a mission to maximise every donated dollar.
Making the first hour of your day high-cortisol and the last hour low-cortisol is described as the single most impactful daily habit for mood, focus, alertness, stress resilience, and sleep quality.
A Washington University in St. Louis study found that a great night's sleep produces attention-improvement effects effectively equal to Ritalin.
In the 4 to 6 hours after exercise, dopamine and norepinephrine are elevated, making you more alert and better able to focus — unless you've exercised to exhaustion.
The physiological sigh — two big inhales followed by a full exhale — was discovered by physiologists in the 1930s and is the fastest way to reduce autonomic arousal.
Doing just 10 deliberate exhales throughout the day can significantly elevate heart rate variability by the evening, by repeatedly activating the vagal sinoatrial node pathway.
For nicotine to have a genuine cognitive-enhancing effect rather than merely rescuing withdrawal deficit, Huberman recommends using it only once or twice per week at 3–6 mg.
Because vaping can be done anywhere and is more palatable, people consume far more nicotine via vaping than they ever did smoking, potentially making vaping more dangerous in aggregate despite being safer per puff.
Huberman reported that two injections of approximately 100–200 micrograms of BPC-157 eliminated persistent shoulder pain that had resisted months of other interventions.
Huberman reported that on nights he used the peptide pinealon, he achieved 2.5 to 3 hours of REM sleep inside 6 hours — an unusually high proportion normally only found in the final hours of longer sleep.
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