Annie Duke had completed five years of her PhD, had job talks lined up, and then a chronic illness landed her in hospital for weeks. She cancelled everything and eventually started playing poker to pay rent. By 1999 she was the winningest woman in the game. By 2002 she was on TV. The TV appearance led to corporate speaking, which led to books, which led to a consulting career she loves. The 'worst luck' she ever had was the founding event of everything she built.