SOLVED with Mark Manson

Podbit · SOLVED with Mark Manson

How to Overcome Anxiety, Solved

Explore episode May 6, 2026
Health & Fitness
CBD: 8 Usable Studies Out of 1,550

How to Overcome Anxiety, Solved · May 6, 2026 Health & Fitness

A 2024 meta-analysis screened 1,550 CBD research papers and found only 8 good enough to include — covering just 316 people total. Even those 8 had a confidence interval so wide that researchers could only say it's either great or does nothing. The $5 billion CBD market runs on almost zero real science.

Where this was said

#14 CBD — $5 Billion Market, Almost No Evidence

At 39:00 · chapter starts 38:10

CBD commands a $5 billion market, but the underlying science is nearly nonexistent for anxiety. Drew walks through a 2024 meta-analysis that screened 1,550 research papers and found only 8 met quality criteria, covering 316 people total. Even those 8 produced a confidence interval so wide that researchers concluded the effect size was 'either amazing or basically nothing.' Two additional problems compound the issue: some studies found that exactly 300mg is required (while commercial products offer 10–50mg), and a 2022 study found that barely half of 80 tested products actually contained their labeled CBD dose. Manson concludes it's likely placebo, and the pair discuss how it reached peak hype in the late 2010s before gradually fading.

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