A 2024 meta-analysis screened 1,550 CBD studies but could only include 8 due to poor quality, covering just 316 participants total — making the evidence base essentially meaningless.
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At 39:33 · chapter starts 38:10
CBD commands a $5 billion market, but the underlying science is nearly nonexistent for anxiety. Drew walks through a 2024 meta-analysis that screened 1,550 research papers and found only 8 met quality criteria, covering 316 people total. Even those 8 produced a confidence interval so wide that researchers concluded the effect size was 'either amazing or basically nothing.' Two additional problems compound the issue: some studies found that exactly 300mg is required (while commercial products offer 10–50mg), and a 2022 study found that barely half of 80 tested products actually contained their labeled CBD dose. Manson concludes it's likely placebo, and the pair discuss how it reached peak hype in the late 2010s before gradually fading.
A 2024 meta-analysis screened 1,550 CBD research papers and found only 8 good enough to include — covering just 316 people total. Even those 8 had a confidence interval so wide that researchers could only say it's either great or does nothing. The $5 billion CBD market runs on almost zero real science.
A 2022 study of 80 commercially available CBD products found that just over half actually contained the amount of CBD stated on their labels.
The U.S. Surgeon General's 2023 report on loneliness found that half of American adults report feeling lonely, marking a widespread epidemic of social isolation.
In a peer-reviewed study, Brain.fm's audio technology was shown to increase focus-related brainwave activity by 119%, according to the show's sponsor read.
The Easterlin Paradox shows that wealthier nations — and the wealthiest neighborhoods within them — tend to have the highest rates of anxiety, depression, loneliness, and suicide.
Mental health challenges are nearly universal — BetterHelp's own research found the majority of Americans experiencing symptoms right now.
When applying for Medicaid to cover nursing home costs, there is a 5-year look-back period that can disqualify applicants who gave away or spent down assets.
A broken pipe filled the Bad Friends studio with what the hosts identified as hydrogen sulfide — microscopic fecal aeroparticles — that the crew denied smelling.
Fei-Fei Li's father's liver surgery performed by a da Vinci robot resulted in 10 times less blood loss than a typical open liver surgery, thanks to laparoscopic precision.
Approximately 115 million adults in the US currently have prediabetes, most of whom are unaware, according to the Lingo sponsor segment.
Drug overdose deaths in the US fell from 110,000 to 80,000 in 2024, and then to roughly 70,000 — the largest single-year drop the CDC has ever recorded.
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