#394 ‒ Sleep pharmacology: the role of medications in healthy sleep, the promise of emerging therapies, and the evidence for common sleep supplements

Ep 624 - Big Boy (feat. Nate Marshall) · Jul 16, 2026 Health & Fitness

Brian Johnson drained his son's blood plasma to inject into himself and wears an umbrella from the sun — but he also publishes all his biohacking data transparently. Matt McCusker coins the term 'healthy vamp' and admits he respects the hustle even if the optics are terrible. Expand

Leading Cancer Researcher: They’re Ignoring My Research, Ca… · Jul 16, 2026 Health & Fitness

Mainstream oncology has operated on the wrong theory for 100 years. Cancer is not primarily a genetic disease driven by DNA mutations — it is a mitochondrial metabolic disease. When mitochondria become chronically damaged, cells fall back on ancient, oxygen-independent fermentation pathways, triggering the dysregulated cell growth we call cancer. Expand

Leading Cancer Researcher: They’re Ignoring My Research, Ca… · Jul 16, 2026 Health & Fitness

Dozens of completely different agents — carcinogens, viruses, chronic inflammation, sleep apnea, radiation — all produce cancer. The paradox is how. The answer: they all damage the same thing. Every single cancer-causing agent chronically impairs mitochondrial oxidative phosphorylation, forcing cells into fermentation and dysregulated growth. Expand

Leading Cancer Researcher: They’re Ignoring My Research, Ca… · Jul 16, 2026 Health & Fitness

Under an electron microscope, cancer cells reveal ghost mitochondria — shells with nothing inside, or grotesquely deformed inner structures. Every cancer cell ever examined shows defects in the number, structure, and function of its mitochondria. Structure determines function: if the organelle is broken, it cannot produce energy properly. Expand

Leading Cancer Researcher: They’re Ignoring My Research, Ca… · Jul 16, 2026 Health & Fitness

Cancer cells cannot burn fat or ketones because their mitochondria are broken. They can only survive on two fuels: glucose (sugar) and glutamine (the most abundant amino acid in the bloodstream). This is why metabolic therapy targets both simultaneously — restrict glucose with ketosis, then target glutamine with repurposed drugs. Expand

Leading Cancer Researcher: They’re Ignoring My Research, Ca… · Jul 16, 2026 Health & Fitness

Niger, Gambia, and Nepal have almost no cancer. Australia, New Zealand, and the US have the most. The difference is modern lifestyle — processed carbs, inactivity, stress, and toxic chemicals constantly damaging mitochondria. Wolves in the wild almost never get cancer. Domestic dogs die from it. Same biology, different environment. Expand

Leading Cancer Researcher: They’re Ignoring My Research, Ca… · Jul 16, 2026 Health & Fitness

The Glucose Ketone Index divides blood glucose (converted to mmol/L) by blood ketone level. A low number means your cells are burning fat efficiently — like Paleolithic man. A high number means you are in the 'red zone' of chronic disease risk. You can measure it yourself with a $30 finger-prick device. Expand

Leading Cancer Researcher: They’re Ignoring My Research, Ca… · Jul 16, 2026 Health & Fitness

When cancer patients enter nutritional ketosis before chemotherapy, tumour cells lose their metabolic shield — the lactic acid and succinic acid waste that normally protects them. The result: far lower doses of chemo achieve much greater effect, while healthy cells are protected by their ability to slow down. Istanbul clinics are already doing this with pancreatic cancer patients surviving 4–5 years. Expand

Leading Cancer Researcher: They’re Ignoring My Research, Ca… · Jul 16, 2026 Health & Fitness

Stem cell tumours cannot metastasize. The cells that spread are different: hybrid cells formed when immune macrophages fuse with tumour stem cells. These hybrids are programmed to roam the body — and they are glutamine-driven. Target their glutamine supply and you can intercept metastatic cancer where it travels. Expand