Podbit · The Diary Of A CEO with Steven Bartlett
In a study from Dr. Candow's lab, healthy young female athletes slept an average of 1 hour longer on training days when taking creatine versus placebo. If replicated in males, this could be one of creatine's most universally appealing benefits.
Where this was said
At 45:28 · chapter starts 41:50
Adding 5g of creatine to antidepressants doubled remission rates in women with major depression over 8 weeks. A 200,000-person study linked low dietary creatine to higher depression rates.
A study of 20 Alzheimer's patients found 20g of creatine daily for 8 weeks increased brain creatine levels by 11% and improved cognitive test scores.
Adding 5g of creatine to a standard antidepressant doubled remission rates in women with major depression over 8 weeks. People with depression consistently show lower baseline brain creatine, and supplementation appears to restore the bioenergetics that underlie mood regulation.
Adding 5g of creatine daily to standard antidepressant treatment doubled remission rates in women with major depression over 8 weeks.
A study of over 200,000 adults found those who consumed the least creatine in their diet had the highest rates of depressive symptoms.
A study in young female athletes found they slept an average of 1 hour longer on training days when taking creatine compared to a placebo.
AI nailed Andrew Huberman's vertigo-vs-low-blood-pressure diagnosis because that pattern has been reported millions of times. But every patient's liver is different and data on liver surgeries is scarce worldwide — making solo robot surgery dangerous. The rule is simple: data abundance means AI can help; data scarcity means keep the human in the loop.
Fei-Fei Li's father had liver surgery performed by a da Vinci robot guided by a surgeon. The result: 10 times less blood loss than a typical procedure. This isn't replacement — it's the gold standard of human-machine collaboration, where the human's judgment and the robot's precision combine.
US drug overdose deaths fell from 110,000 to roughly 70,000 — the biggest CDC-recorded single-year drop ever. Men's rates fell 27% in one year, and the steepest decline of all was among 15–24-year-olds, down 37%. The crisis narrative around young men needs to make room for signs of genuine progress.
Kessler thought his grief expertise would protect him. It didn't. When his son David died unexpectedly, he found himself on the floor — and eventually realized that acceptance alone wasn't enough. That unmet need became the sixth stage: finding meaning.
Grief isn't just death — it's any unwanted change. Kessler lectured at Coca-Cola and General Mills not because they had lots of funerals, but because change management is grief management. People who grieve well live well.
Witnessing someone's grief isn't just emotional support — it's an essential act of healing. Kessler argues grief is a severance and connection heals it. But real witnessing has two steps: seeing the pain AND affirming the person's capacity to recover.
Avoiding grief isn't free — it's exhausting. Kessler's beach ball metaphor nails it: pushing a small balloon down is easy, but holding a massive beach ball underwater takes constant, draining energy. Unattended feelings don't disappear; they just consume you.
Most people try to control their environment to avoid triggers. Kessler flips this entirely: triggers aren't problems to manage around — they're a detailed map to your pain and your healing. Every trigger points directly to what needs attention.
Running from pain doesn't leave it behind — it accelerates the chase. Whatever we run from pursues us, and whatever we face transforms us. Both Kessler and Lewis Howes testify to knowing both roads firsthand.
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