Armchair Expert with Dax Shepard

Podbit · Armchair Expert with Dax Shepard

Edward Norton Returns Again

Explore episode Jul 1, 2026
Science
Epigenome Anti-Aging: The First Human Trial Has Begun

Edward Norton Returns Again · Jul 1, 2026 Science

Aging isn't in your DNA — it's in your epigenome, the layer above DNA that switches genes on and off and accumulates errors over time. Scientists have already reversed aging in mice by pruning the epigenome back to a pre-error state. The first human trial has now started. It is genuinely conceivable that people will one day select their own biological age.

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Human learning moves at generational speed — like elephants, one cycle per 15–20 years. Geneticists study fruit flies because they produce two generations a day, compressing evolution into observable timeframes. AI is doing the equivalent: compressing thousands of generations of learning into near real-time iteration.

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Black Holes: What Actually Happens to Your Body

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