Huberman Lab

Podbit · Huberman Lab

Essentials: The Science & Treatment of Bipolar Disorder

Explore episode Jul 16, 2026

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Bipolar Disorder

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Andrew Huberman opens this Huberman Lab Essentials episode with a clear-eyed statement of purpose: bipolar disorder is serious, affecting roughly 1 in every 100 people and carrying a 20 to 30 times elevated suicide risk. He introduces himself as a professor of neurobiology and ophthalmology at Stanford School of Medicine, immediately grounding the conversation in clinical authority. Bipolar disorder, he explains, involves massive maladaptive shifts in energy, perception, and mood — not the kind of highs and lows that most people casually associate with emotion. He emphasizes that these shifts cause tremendous harm not only to the individual but to everyone in their orbit. The episode is framed as essential for anyone who has bipolar disorder, suspects they might, or cares about someone who does.

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