Speaker
Andrew Huberman
Appearances over time
13 episodes
Episodes
13
Your Top Health Questions Answered
Accelerate Learning & Increase Cognitive Capacity | Dr. Tommy Wood
Essentials: The Science & Treatment of Bipolar Disorder
How to Improve Your Memory & Cognitive Function at Any Age | Dr. Alan Castel
Essentials: The Science & Treatment of Obsessive Compulsive Disorder (OCD)
Movement Practice to Strengthen Your Mind-Body Connection | Ido Portal
Essentials: The Science of Eating for Health, Fat Loss & Lean Muscle | Dr. Layne Norton
Science of Attraction, Compatibility & Romance | Dr. Paul Eastwick
Essentials: Improve Flexibility with Research-Supported Stretching Protocols
The Mental Frame & Specific Daily Actions to Succeed | Andy Stumpf
Essentials: The Science & Process of Healing from Grief
Mostly Wise: Matt McCusker, Andrew Huberman & Tom Segura - #1102
The Effects of Microplastics on Your Health & How to Reduce Them
Podcasts
Quotes & moments
A 2024 PNAS study using improved imaging found bottled water contains on average 240,000 microplastic and nanoplastic particles per liter, far exceeding the prior estimate of 30,000.
Flexibility and stretching involve neural, muscular, and connective tissue components working together in a loop.
Alpha-GPC is the only supplement Andrew Huberman knows of that can increase alertness and workout intensity while also modestly increasing REM sleep rather than harming it.
Stanford's chair of male sexual health Mike Eisenberg recommends nearly every man over 40 take low-dose tadalafil daily for prostate perfusion and brain vasodilation.
The brain maps all relationships across space (physical proximity), time (when you expect to see them), and closeness (depth of attachment), all processed by the inferior parietal lobule.
OCD affects an estimated 2.5% to as high as 4% of people, making it an astonishingly common condition.
Bipolar disorder affects approximately 1% of the population, meaning roughly 1 in every 100 people is likely to have the condition.
Golgi tendon organs sense excessive load and can inhibit motor neurons to prevent muscle or tendon damage — a built-in safety override.
A single brain area — the inferior parietal lobule — is uniquely activated by changes in physical spacing, temporal spacing, and emotional closeness, forming the neural basis of all attachment.
Alpha-GPC can raise TMAO levels, which carries cardiovascular risk; pairing it with 600mg of garlic (allicin) can help inhibit TMAO production.
People with bipolar disorder face a 20 to 30 times greater risk of suicide compared to the general population.
Postmortem analysis of adult human brains found microplastics and nanoplastics make up approximately 0.5% of total brain weight — roughly a teaspoon of salt's worth.
OCD is currently ranked number 7 among all illnesses — not just mental disorders — in terms of overall debilitation, outranking conditions like asthma and many cancers.
Low-dose tadalafil may increase the number or sensitivity of androgen receptors, helping the body respond better to circulating testosterone.
A randomized crossover trial found that eating one serving of canned soup daily for five days was associated with more than a 1,000% increase in urinary bisphenol A (BPA).
Marc Andreessen publicly endorsed an internet figure called 'retardmaxx' who advocates for just handling your business without rumination. The counterintuitive argument: great historical figures weren't known for introspection — they were known for action. Sometimes the highest-performance move is to stop thinking and start doing.
After a high-stimulus performance, catecholamines (dopamine, norepinephrine, epinephrine) are cranked to 11. Orgasm triggers a prolactin surge that hammers dopamine down and shifts the nervous system into parasympathetic rest mode. Evolution hardwired this circuit — comedians just discovered it empirically.
Hot shower before bed lowers core body temperature via compensatory thermoregulation. Long deliberate exhales activate the vagus nerve and slow heart rate. A magnesium-saffron-apigenin stack handles the supplement side. For advanced users: pinealon peptide, 3 nights a week, from a compounding pharmacy — Huberman calls the REM sleep effect 'spectacular'.
Research shows that just seeing a great sleep score improves cognitive and physical performance the next day — even if the sleep was mediocre. The reverse is equally true. The implication: checking your Whoop every morning might be sabotaging you on bad days more than it helps you on good ones.
Love Island producers removed all clocks, changed car radio times, and took watches away from contestants to control their sleep-wake cycles. Chris Williamson connected this to Huberman's research on how manipulating sleep scores shapes behavior — Love Island was running an unsanctioned circadian experiment on its cast.
People are uploading years of text message history and photos into AI chatbots to recreate their exes. One woman says it satisfies her emotional needs and prevents her from rebooting contact. The concern: it keeps you perfectly frozen in the relationship, perpetually preventing closure — and your ex may own their likeness over that data.
The classic serial killer era of BTK, Bundy, and Dahmer required time, mobility, and anonymity. Ring doorbells, toll cameras, phone GPS, and omnipresent CCTV have eliminated all three. Criminals now get caught so fast that long-running sprees are essentially impossible.
Matt McCusker pointed out that falling is a multi-billion dollar lawsuit industry in the US — illustrated by a viral video of a man deliberately crawling under a collapsed gas station awning to fake an injury claim. Russell Peters' brother similarly got treated like a crime victim when he slipped at CBS because America is uniquely litigious about slips and falls.
Eleven Labs' flagship British AI voice 'Archer' is — based on a side-by-side comparison — trained heavily on Chris Williamson's voice. It's already being used in unauthorized product ads. Eleven Labs told his team the similarity score was too low to act on. Huberman says he has IP lawyers who can fix this.
Huberman defines clang associations — a symptom of psychosis where people link ideas by sound or visual similarity rather than evidence. In the wellness world, this shows up as 'walnuts look like a brain so they must be good for your brain.' He's not diagnosing people — but this pattern of thinking is a warning sign.
UV light is the enemy, but long-wavelength infrared and red light from the sun are critical for mitochondrial health and can even penetrate clothing. Use zinc oxide–only mineral sunscreen to block UV while preserving infrared benefits, avoid burning, and get natural sunlight especially in early morning and late afternoon when the UV index is low.
In the original Stanford marshmallow test, no child waited the full 15 minutes — a fact that never gets mentioned. Yet how long kids waited before eating still predicted better life outcomes. The finding does hold up under replication, and self-control can be built — but the common telling strips out important nuance.
Johnny Depp spent his entire reported $650 million fortune. The highlights include $75 million on 14+ residences, $30–40k/month on wine, and $3 million to blast his friend Hunter S. Thompson's ashes from a custom cannon. His comeback via the new Pirates of the Caribbean could earn him 9 figures from a gross revenue deal.
Tom Segura laid out the legitimate forensic case against the Epstein suicide ruling: he changed his will days before death, his hyoid bone broke in a way forensic pathologists say is more consistent with homicide than suicide, and narcissists statistically don't kill themselves. Huberman notes the government is inefficient at covering things up, but 'I don't know' remains the most honest answer.
Low-dose tadalafil (2.5–5 mg/day) isn't just for erectile dysfunction. Stanford's chair of male sexual health says most men over 40 should take it for prostate perfusion, brain vasodilation, and upregulation of androgen receptors. The patent expired — it costs pennies as a generic.
Analysis
What they talk about
- Health & Fitness 66%
- Society & Culture 15%
- Science 12%
- Education 2%
- History 2%
- Technology 1%
- Sports 1%
- Business 1%
Connections
Shows they appear on and people they share episodes with. Drag to explore.
