25% GLP-1 users report sexual side effects
A survey of 1,000 women who had taken GLP-1 weight-loss drugs found that about 25% reported sexual side effects.
Snapshot · The Diary Of A CEO with Steven Bartlett
Dr Rachel Rubin: Women’s Sexual Health, Menopause, Hormone Replacement Therapy (HRT), and Orgasms!
Explore episode
Jun 22, 2026
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How GLP-1s And Antidepressants Affect Sex Drive
At 18:08 · chapter starts 16:25
The combined pill shuts down ovaries, which make estrogen, progesterone, AND testosterone. The pill adds back the first two but not testosterone, suppressing libido in up to 27% of users. [1] — Dr Rachel Rubin "The combined birth control pill works by flooding the body with synthetic hormones so high that the ovaries stop producing their own. But o…" 15:05
27% libido drop on birth control
In some studies, up to 27% of people on birth control report a decrease in libido or sex drive.
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