There are now 25 randomized controlled trials showing saffron is as effective as SSRIs and other antidepressants, with a better side effect profile and no reduction in sexual function.
Snapshot · The Diary Of A CEO with Steven Bartlett
There are now 25 randomized controlled trials showing saffron is as effective as SSRIs and other antidepressants, with a better side effect profile and no reduction in sexual function.
Where this was said
At 37:13 · chapter starts 33:01
A viral graph showing the US prescribes far more antidepressants per capita than any other nation prompts a deep dive into why. Amen's diagnosis: America wants a fast fix, and it's getting it — from the wrong people. 85% of psychiatric medications are dispensed by non-psychiatric physicians in 7-minute office visits that meet standard of care only 12% of the time. The result is patients walking out with Lexapro, Xanax, and Ambien from a single rushed appointment. What bothers Amen most is a pharmacological reality few patients are told: SSRIs don't heal the brain. They suppress symptoms while chemically rewiring the brain to need them in order to feel normal. Against this backdrop, he lays out four interventions that have matched antidepressants in direct head-to-head trials: saffron (the subject of 25 randomised controlled trials, which also enhances memory and sexual function); brisk walking 45 minutes four times a week; omega-3 fatty acids; and learning not to believe every automatic negative thought. [1] — Dr. Daniel Amen "85% of psychiatric drugs prescribed by non-psychiatrists: In America, 85% of psychiatric medications are prescribed by non-psychiatric phys…" 33:30 His argument is not anti-medication — it's pro-sequencing: start with these interventions first, and reserve pharmaceuticals for cases where they're genuinely needed.
In America, 85% of psychiatric medications are prescribed by non-psychiatric physicians in 7-minute office visits, with standard of care being met only 12% of the time.
Saffron, brisk walking 45 minutes four times a week, omega-3 fatty acids, and cognitive therapy have all been shown in head-to-head trials to be as effective as antidepressants. Saffron also enhances memory and sexual function — and doesn't rewire your brain to need it.
Spencer Greenberg and Jeremy Stevenson analyzed almost 500 self-improvement techniques and found they all reduce to just 12 underlying psychological drivers.
Cold exposure has good short-term alertness benefits but the evidence base for long-term health benefits is much weaker than popularly believed.
In a randomized study of 20 habit-formation techniques run on hundreds of people, almost none of the techniques produced statistically meaningful results.
People given a tiny-habit fallback option (e.g. 10 squats instead of gym) were actually MORE successful at completing the full habit, not less.
The most effective habit-formation technique was 'habit reflection' — recalling a past successful habit, writing down what helped, then applying those lessons to a new habit.
A study found that simply scheduling enjoyable activities was as effective as standard cognitive behavioral therapy for depression, leading to its own therapy called behavioral activation.
The 'worry time' technique — deferring all worries to a designated time of day — helps people realize they have more control over worry than they thought and reveals it is less useful than it feels.
A study found that participants told to try to stay awake while in bed fell asleep faster than participants told to try to sleep — illustrating the paradox of direct effort.
Spencer Greenberg reduced his severe social anxiety dramatically in roughly 6 months through a structured exposure therapy hierarchy, culminating in asking strangers for hugs.
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