Blood work every 6 months
Dr. Kyle Gillett recommends that men get hormone blood work done roughly every 6 months in consultation with their physician.
Snapshot · Huberman Lab
Essentials: Tools for Hormone Optimization in Males | Dr. Kyle Gillett
Explore episode
Jul 2, 2026
Where this was said
Male Hormone Optimization, Testosterone, Tool: Blood Tests
At 2:11 · chapter starts 0:20
Dr. Gillett frames hormone monitoring as akin to hooking a new car up to a diagnostic computer at the assembly line — humans deserve the same systematic tracking across a lifetime of development. Andrew Huberman prompts a breakdown of what that bloodwork should actually include, and Gillett zeros in on the trio of total testosterone, SHBG, and free testosterone as the essential starting panel. He defines SHBG — the protein that binds androgens and estrogens, with stronger androgens binding more tightly — and explains the balance between total and free DHT during puberty. Importantly, he recommends men revisit these panels roughly every 6 months in shared decision-making with their physician, establishing a baseline surveillance rhythm rather than reactive testing.
Why Every Man Should Get Hormone Bloodwork Done
Just like a new car gets hooked up to a diagnostic computer, men should monitor hormone development throughout life. Testosterone, SHBG, and free testosterone are the key starting markers, and a 6-month follow-up cadence with a physician is the baseline standard.
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