Aspartame (NutraSweet) is found in over 500 diet foods and sodas in the US food supply, and mouse studies show it may induce heritable anxiety disorders across two generations.
Snapshot · On Purpose with Jay Shetty
Aspartame (NutraSweet) is found in over 500 diet foods and sodas in the US food supply, and mouse studies show it may induce heritable anxiety disorders across two generations.
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At 1:16:40 · chapter starts 1:07:31
Palmer traces the arc of his own career disillusionment and recovery. When he entered psychiatry he became, by his own admission, 'one of those evil psychiatrists who just doled out pills' — because those were the only tools he had, and people's lives were in danger. He maintained skepticism throughout, asking himself whether what he was doing was any better than what was done for his mother. Now, he says, he has found real reasons for hope: a coherent theory of metabolic dysfunction, actionable interventions like the ketogenic diet, and 20 controlled trials underway. [1] — Dr. Chris Palmer "20 controlled trials of keto for mental health underway: There are currently 20 controlled trials — including 8 randomised controlled trial…" 59:00 His forecast is bold: in 10 to 20 years, he believes we will look back on 2024's psychiatric practices — over-reliance on medications that don't produce remission, failure to address root causes — as almost barbaric. He frames this not with bitterness but with urgency, noting he is in his 50s and believes he has enough time left to see that transformation begin.
Parents focus on love, safety, independence, and community — but almost universally overlook nutrition as a factor in their child's brain health. Ultra-processed foods don't just deprive kids of nutrients; they actively deliver brain-disrupting chemicals. This is the last great parenting blind spot.
Mouse studies show aspartame induces anxiety-like behavior, confirmed by amygdala hyperactivation. More alarming: those anxiety-like behaviors persisted in offspring for two generations without any direct aspartame exposure. If your mother drank Diet Coke, you may have inherited her anxiety.
Spencer Greenberg and Jeremy Stevenson analyzed almost 500 self-improvement techniques and found they all reduce to just 12 underlying psychological drivers.
Cold exposure has good short-term alertness benefits but the evidence base for long-term health benefits is much weaker than popularly believed.
In a randomized study of 20 habit-formation techniques run on hundreds of people, almost none of the techniques produced statistically meaningful results.
People given a tiny-habit fallback option (e.g. 10 squats instead of gym) were actually MORE successful at completing the full habit, not less.
The most effective habit-formation technique was 'habit reflection' — recalling a past successful habit, writing down what helped, then applying those lessons to a new habit.
A study found that simply scheduling enjoyable activities was as effective as standard cognitive behavioral therapy for depression, leading to its own therapy called behavioral activation.
The 'worry time' technique — deferring all worries to a designated time of day — helps people realize they have more control over worry than they thought and reveals it is less useful than it feels.
A study found that participants told to try to stay awake while in bed fell asleep faster than participants told to try to sleep — illustrating the paradox of direct effort.
Spencer Greenberg reduced his severe social anxiety dramatically in roughly 6 months through a structured exposure therapy hierarchy, culminating in asking strangers for hugs.
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