New Limit, the epigenetic reprogramming company co-founded by Coinbase CEO Brian Armstrong, raised $435 million at a $3.1 billion valuation.
Snapshot · Moonshots with Peter Diamandis
New Limit, the epigenetic reprogramming company co-founded by Coinbase CEO Brian Armstrong, raised $435 million at a $3.1 billion valuation.
Where this was said
At 1:29:45 · chapter starts 1:29:30
Brian Armstrong's New Limit raised $435M at $3.1B to reverse cellular aging. Peter Diamandis discusses the $101M HealthSpan XPRIZE with 830 teams and a 2030 target winner. [1] — Peter Diamandis "New Limit raised $435M at a $3.1B valuation to develop epigenetic reprogramming therapies targeting alcohol-related liver disease as an FDA…" 1:29:25
Peter Diamandis raised $157 million for the $101 million HealthSpan XPRIZE to develop therapies that reverse functional aging by 20 years, with 830 teams entered.
VRRV-102 is a single gene-editing infusion that permanently switches off the PCSK9 gene, cutting LDL cholesterol 62% and sustaining results for 18 months in Phase 1 trials. Dr. Wissner-Gross calls it 'squinting at it — a one-time shot to cure heart disease.'
Despite predictions that AI would eliminate radiologists, the Mayo Clinic's radiology staff grew 55% after AI arrived at reading scans.
In 2025, radiology was the second-highest paid medical specialty in America, with average incomes 48% higher than a decade ago.
A study across 3 hospitals found radiologists spent only 36% of their time reading scans — the part AI can do — with the rest being human judgment.
Robert Greene notes that one in six Americans is on some form of drug to deal with depression, suggesting a deep societal disconnection from meaningful experience.
Spencer Greenberg and Jeremy Stevenson analyzed almost 500 self-improvement techniques and found they all reduce to just 12 underlying psychological drivers.
Cold exposure has good short-term alertness benefits but the evidence base for long-term health benefits is much weaker than popularly believed.
In a randomized study of 20 habit-formation techniques run on hundreds of people, almost none of the techniques produced statistically meaningful results.
People given a tiny-habit fallback option (e.g. 10 squats instead of gym) were actually MORE successful at completing the full habit, not less.
The most effective habit-formation technique was 'habit reflection' — recalling a past successful habit, writing down what helped, then applying those lessons to a new habit.
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