A National Academies study found that researchers spend 45% of their time on administrative grant-related work rather than actual science.
Snapshot · Moonshots with Peter Diamandis
A National Academies study found that researchers spend 45% of their time on administrative grant-related work rather than actual science.
Where this was said
At 34:03 · chapter starts 31:15
The interview pivots to the substantive heart of the Golden Age Report: why, despite record budgets and better tools, is scientific productivity declining? Kratsios traces the problem to institutional inertia — a system designed decades ago that nobody wants to change, especially those who have succeeded within it. [1] — Michael Kratsios "The NIH budget has ballooned to $45 billion yet drugs are more expensive than ever. Researchers spend 45% of their time on grant paperwork.…" 31:30 The data is damning: the NIH budget has swelled to nearly $45 billion yet drugs are more expensive than ever. A National Academies study found researchers spend 45% of their time on grant administration. The median age of an intramural NIH scientist is 71 — while the average age of Nobel-winning scientific work is in a researcher's 20s. The scientific community, Kratsios observes wryly, is perhaps the community least interested in experimenting with new ways of doing science. The irony is not lost on either speaker.
The NIH budget has ballooned to $45 billion yet drugs are more expensive than ever. Researchers spend 45% of their time on grant paperwork. The median intramural NIH scientist is 71. Kratsios argues the problem isn't money — it's that the scientific enterprise refuses to experiment on itself.
Despite NIH's budget growing to nearly $45 billion, the cost of drugs is higher than ever, indicating declining returns on science spending.
Animals first sensed light 540 million years ago, triggering an evolutionary acceleration known as the Cambrian explosion within 10 million years.
It is estimated that half of all cortical activity in the human brain is involved in visual function, underscoring vision's central role in intelligence.
Cognitive neuroscience literature shows that by age 6, humans can recognize tens of thousands of different object categories — far more data than early AI systems were trained on.
Only about 3% of FDA-approved drugs have genuinely unclear mechanisms of action, making an unknown mechanism a meaningful early red flag for any compound.
Even compounds that clear preclinical testing often fail in humans: 30 to 50% of drugs entering phase 1 trials do not advance to phase 2, frequently because human behavior differs from animal models.
More than 80% of published BPC-157 research comes from a single academic group whose researchers have IP and commercial interests connected to the molecule, limiting independent replication.
Roughly 100 peptide drugs are already FDA-approved, about 150 more are in clinical trials, and 600–700 are in preclinical development, underscoring the legitimacy of peptide science broadly.
The scientist who discovered BPC-157 refused to disclose the screening method used to identify the compound and has never fully published the parent protein sequence — what Peter Attia calls 'scientific trust me, bro.'
The brain's visual, auditory, and motor cortices light up nearly identically whether an experience is real or imagined, making visualization a form of actual neural training.
We use essential and analytics cookies to run Vuci. To understand how the site is used: Privacy Policy.
Install Vuci on your phone
Add it to your home screen for a faster, app-like experience.
Install Vuci on your phone
Tap the Share button, then “Add to Home Screen”.
A new version is available
Reload to get the latest Vuci.