Snapshot · Huberman Lab
Yoga practitioners show significantly increased gray matter volume in the insular cortex, the brain region associated with interoception and pain interpretation.
Where this was said
At 32:00 · chapter starts 30:20
The episode's final major scientific chapter returns to the insula and delivers one of its most compelling findings. A study published in Cerebral Cortex — 'Insular Cortex Mediates Increased Pain Tolerance in Yoga Practitioners' — examined yoga practitioners spanning multiple traditions (vinyasa, ashtanga, Iyengar, sivananda) and compared them to non-practitioners on pain tolerance using thermal stimulation. [1] — Andrew Huberman "A study in Cerebral Cortex found yoga practitioners had more than double the pain tolerance of non-practitioners under thermal stimulation,…" 30:00 The result was striking: yoga practitioners had more than double the pain tolerance of controls. Brain imaging revealed the structural reason — significantly increased gray matter volume in the insular cortex. Huberman emphasises that gray matter volume increase indicates more neuronal cell bodies in those regions, implying genuine structural adaptation, not just skill acquisition. Crucially, he argues that the brain changes come not from the movements themselves but from the repeated experience of choosing to stay in discomfort at the end ranges of motion — a form of intentional, controlled overriding of the pain-avoidance instinct. This positions yoga not just as a flexibility tool but as a nervous system training protocol that reshapes pain processing in ways that generalise beyond the mat. He closes by noting the pleasing alignment between this finding and the microstretching data: you don't push to pain to get flexible, but a practice that teaches you to intelligently manage your relationship to discomfort builds a structurally different brain.
A study in Cerebral Cortex found that yoga practitioners had double or more the pain tolerance of non-yoga practitioners when measured with thermal stimulation.
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