The Shawn Ryan Show

Snapshot · The Shawn Ryan Show

#315 Sadhguru - Stop Letting Your Mind DESTROY You

Explore episode Jun 22, 2026

Where this was said

Psychedelics, FDA Approval, and Whether They Are Necessary

At 3:17:50 · chapter starts 3:13:45

Shawn cites Polymarket data giving a 33% probability that the FDA will approve a psychedelic for medical use in 2025, noting Trump's executive order fast-tracking approval for PTSD and depression treatment. Sadhguru has previously said psychedelics are unnecessary. Challenged on this, he does not engage with FDA policy directly but instead uses the question as a pivot back to the nature of trauma and desire. If trauma is resistance to a gap between desire and reality, and if that gap is understood at the level of the desiring phenomenon rather than its objects, then the inner chemistry changes and there is no longer a foothold for trauma. The psychedelic, in this view, offers a temporary chemical change that the person then loses — whereas inner transformation changes the chemistry permanently. He also reveals he was in America just before the Save Soil journey, describing a young man desperately chasing $1 billion while eight friends sat quietly — Sadhguru offered them all $10 billion each, and the young man immediately became miserable. Desire is not about the number: it is about the need to exceed whoever is around you.

Society & Culture
The Prison Transformed by Inner Engineering

#315 Sadhguru - Stop Letting Your Mind DESTROY You · Jun 22, 2026 Society & Culture

For 136 consecutive years, at least one prisoner was sent to solitary confinement every single day in one Indian prison. After Sadhguru's Inner Engineering program became mandatory, the streak ended — and prisoners who had howled through the night began sleeping peacefully. A man on death row started calling his cell his Bodhi tree.

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