Bert Kreischer publicly discloses on stage — in front of a live crowd — that he is taking Mounjaro (tirzepatide) and has lost 50 pounds. He frames it as 'Zoloft for fat people' and challenges the stigma around weight-loss medication in Hollywood.
Podbit · 2 Bears, 1 Cave with Tom Segura & Bert Kreischer
Bert Kreischer publicly discloses on stage — in front of a live crowd — that he is taking Mounjaro (tirzepatide) and has lost 50 pounds. He frames it as 'Zoloft for fat people' and challenges the stigma around weight-loss medication in Hollywood.
Where this was said
At 28:12 · chapter starts 23:40
After Jelly Roll's emotional segment, H. Foley and Kevin Ryan bring the energy back to gleeful chaos. Foley is down 50 pounds and Kevin is down 75, but the real story is Foley's digital collapse: his phone got wet, he forgot his Apple ID, and Apple shut down his Uber, Venmo, Seamless, and every other app simultaneously. Kevin reads the panicked, unpunctuated email Foley sent from a laptop — which includes his Hell's Kitchen address and closes with 'I love you both. Hopefully to talk to you soon, Henry' — to hysterical reaction. [1] — H. Foley "H. Foley's phone got wet, he forgot his Apple ID, and Apple nuked his entire digital life. Kevin Ryan reads aloud the single run-on email F…" 39:27 [2] — H. Foley "H. Foley down 50 lbs: H. Foley from Are You Garbage? shared he is down approximately 50 pounds." 26:05 Between bits, Bert defends himself against Tom's revelation that he appears in the Epstein files ('I was in his email because he was a big fan of comedy'), the gang discovers Bert's Gmail is [email protected] after it was accidentally sent to the Girl Scouts, and Bert delivers a vivid account of his first bidet experience in Japan that escalated quickly.
H. Foley from Are You Garbage? shared he is down approximately 50 pounds.
Kevin Ryan from Are You Garbage? revealed he has lost 75 pounds.
Bert Kreischer revealed his DEXA scan showed he was 40% body fat, while his wife Leanne was 22%.
Bert Kreischer publicly disclosed he is taking Mounjaro (tirzepatide) and has lost 50 pounds, calling it like 'Zoloft for fat people.'
H. Foley's phone got wet, he forgot his Apple ID, and Apple nuked his entire digital life. Kevin Ryan reads aloud the single run-on email Foley sent from his laptop, including his Hell's Kitchen address and a heartfelt sign-off of 'Henry.'
Spike your cortisol in the first 1–3 hours of your day — with sunlight, hydration, exercise, or caffeine — and you set up elevated mood, focus, and stress resilience for the rest of the day. Miss that spike and you get a flat cortisol curve: brain fog, poor learning, and bad sleep. The bookend is equally important: dim lights, no caffeine, and wind down the final hour.
Bottom-up impulses — just eat the cookie, keep scrolling — are driven by deep brain structures. Top-down prefrontal control is the thing that lets you wait, learn, and grow. Every small act of choosing the harder thing, from picking up trash to doing the workout you dread, greases that top-down circuit — and it transfers to everything else.
A Washington University in St. Louis study found that the attention-improvement effects of Ritalin are effectively equal to a great night's sleep. Stimulants also stunt growth and reduce sleep quality. The new direction is combining lower medication doses with genuinely better sleep — not replacing sleep with pharmacology.
Two big inhales through the nose, then a full exhale to empty — that's the physiological sigh. It fires a specific vagal pathway to slow your heart rate, offload CO2, and tip the autonomic nervous system toward calm instantly. Doing just 10 deliberate exhales throughout the day measurably elevates HRV by nighttime.
Presence isn't a state you fall into — it's something you actively produce by anchoring perception to the immediate environment. Ask 2–3 trivially specific questions about your surroundings (how many cans, what does it smell like) to pull your brain out of past/future mode. Then deliberately choose what to think or say next. That's it.
Acknowledge the thing, feel all of it, uncouple the emotion from the memory, then transmute the experience into something meaningful. Most people stall at step 2 — feeling the feelings — and never reach uncoupling. An entire generation is stuck there, confusing emotional processing for healing. Moving through all four is the actual path out.
Nicotine creates a uniquely alert-and-calm state ideal for learning — but only at low doses used occasionally. If you're using 3–6 mg pouches multiple times a day, you're not getting a cognitive enhancement, you're just rescuing yourself from withdrawal. For a genuine performance effect, use it once or twice per week at most.
Two injections of BPC-157 (100–200 mcg) eliminated shoulder pain Huberman couldn't shift for months. The peptide pinealon gave him 2.5–3 hours of REM sleep inside 6 hours — an effect that persisted into subsequent nights and scaled down to just once per week. Neither is in the book because the human data aren't there yet, but the animal evidence is strong.
Long, slow cardio builds capillary networks and mitochondrial richness; high-intensity intervals push VO2 max. You don't need huge volumes of either. Huberman's protocol: one 45–60 minute long slow session, one near-maximal effort HIIT session (Airdyne 20-on/10-off for 6–8 rounds), and one medium 30-minute effort per week. That's the complete cardio picture.
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