Quote · Modern Wisdom

Matt McCusker, Andrew Huberman & Tom Segura - Mostly Wise #1 - #1102

Explore episode May 25, 2026

As dopamine goes up, testosterone goes up in women and men. And then after orgasm, dopamine goes down and a hormone, which is basically a hormone prolactin, goes up, and that sets the refractory period, during which time you need a higher stimulus thing to get you aroused.

Andrew Huberman

Matt McCusker, Andrew Huberman & Tom Se…

Where this was said

The Unexpected Benefits of Fap Naps

At 1:38:00 · chapter starts 1:31:10

Health & Fitness

The Neuroscience Behind the Fap Nap

Matt McCusker, Andrew Huberman & Tom Segura - Mostly Wise #… · May 25, 2026 Health & Fitness

After a high-stimulus performance, catecholamines (dopamine, norepinephrine, epinephrine) are cranked to 11. Orgasm triggers a prolactin surge that hammers dopamine down and shifts the nervous system into parasympathetic rest mode. Evolution hardwired this circuit — comedians just discovered it empirically.

I get up in the morning, and there's like this narrow path. And on either side, it's just like, woah, down to no productivity, nothing useful in life. One side is drama, other people's drama. And the other side is just numbing out.

Andrew Huberman

Matt McCusker, Andrew Huberman & Tom Se…

The algorithms are very, very good. And so you go, alright, well, I've been good to Adam, so I get on for a second. And it'll be like fight video on X. It's just insane. And then you're like, I don't want to see this. You'll go and it'll be like, cute video. And it'll find your button. It will just find it.

Andrew Huberman

Matt McCusker, Andrew Huberman & Tom Se…

Health & Fitness

Fap nap: universal comic recovery tool

Matt McCusker, Andrew Huberman & Tom Segura - Mostly Wise #… · May 25, 2026

Tom Segura and Matt McCusker confirm that masturbation after a high-stimulus performance is a widely used method among comedians to come down from the adrenaline spike and fall asleep.